• Start low and go slow, especially if you are new to using DMT. If possible, weigh out your doses.

• A DMT trip can be influenced by your environment. Choose a space where you feel comfortable, safe and in control.

• Choose a time where you have few commitments or responsibilities for the duration of the trip.

• If desired, set a timer as a reference point, since DMT causes time distortion.

• If possible, use in the presence of a trusted friend who knows what you are taking and how much.

• People with mood disorders may be at increased risk of psychological upset when smoking DMT.